Following description taken from Fox website.
Prison Break

Just when they thought they were out, they are pulled back in – for the most dangerous escape ever. Entering its dramatic and action-packed third season, PRISON BREAK finds MICHAEL SCOFIELD (Wentworth Miller) wrongly incarcerated in Sona, a hellish Panamanian prison where there are no rules, no guards and no escape.

After successfully breaking his older brother LINCOLN BURROWS (Dominic Purcell) out of Fox River Penitentiary for a murder he did not commit (Season One), Michael, Lincoln and several other convicts were the targets of a nationwide manhunt that eventually led them to tropical Panama (Season Two).